This edition is devoted to Brain Damage and Repair. Topics include basic mechanisms involved in brain injury occurring in various neurodegenerative diseases (Alzheimer, Parkinson, Huntington, amyotrophic lateral sclerosis, fronto temporal lobar dementia), stroke and brain/spinal cord trauma. These appalling disorders constitute a devastating problem for patients, their families and society in general. Population aging is increasing in developed countries and so will be the incidence and prevalence of some neurodegenerative diseases and stroke in which aging is a relevant risk factor. These diseases constitute a huge economical burden and loss of quality of life of patients and caregivers.