The intention of the course is to provide practical training in important aspects of using solution state NMR spectroscopy for studying the structure, dynamics and function of biomolecular macromolecules. The emphasis will be on setting up experiments on the spectrometer (optimizing parameters, pulse programs), on processing and analyzing the NMR data and on structure calculations in a hands-on fashion. Topics covered include: triple resonance pulse seuqences, RDCs, NMR relaxation measurements and data analysis, PREs, structure calculation and validation.

The course is aimed at PhD students and postdocs who have some working knowledge of NMR theory, i.e. product operator formalism, and who understand the basic principles of NMR pulse sequences. Possible candidates should have the level of knowledge of students that have participated in a past "Advanced NMR" EMBO lecture course on NMR theory organized by Boelens, Oschkinat and Griesinger.