Cordis events

Synaptic computations of the hippocampal CA3 circuitry

The hippocampus is critical for learning and memory, and the unique wiring of its CA3 area has inspired theories for neuronal mechanisms of memory storage and retrieval. CA3 pyramidal neurons form an interconnected network which could store unique experiences in specific...

Publication date
10 Mar 2021

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Visualisation of translation initiation reaction on single mRNA molecules in vivo

Translation initiation is a key step in the regulation of protein synthesis and is regulated by at least 12 different initiation factors in eukaryotes (eIFs). However, the underlying dynamics of this process remain unclear. I propose to develop a single-molecule live-cell...

Publication date
10 Mar 2021

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The role of Polycomb Repressive Complex 2 (PRC2) in plant acclimation to ambient light

Polycomb Repressive Complex 2 (PRC2) is an evolutionarily conserved histone methyltransferase complex that catalyses trimethylation of lysine 27 of histone H3 (H3K27me3), which leads to epigenetic gene repression. In Arabidopsis thaliana (A. thaliana), CURLY LEAF (CLF) and...

Publication date
10 Mar 2021

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Soft Template Mediated Peptide Crystallisation

Peptides are recognised for being highly selective and efficacious signalling molecules that bind to the specific cell surface receptors or ion channel where they trigger intracellular effects. They are relatively safe compared to small molecule-based drugs and are well...

Publication date
10 Mar 2021

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Nonlinear spatiotemporal light bullets: origin and stability

The NOSTER project is about unveiling the dynamics and features of spatiotemporal coherent structures emerging in multimode optical fibers, such as spatiotemporal solitons, also known as light bullets. Solitons are particle-like states, emerging due to a double balance...

Publication date
10 Mar 2021

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DOVETAILED MASSIVE WOOD BOARD ELEMENTS FOR MULTI-STORY BUILDINGS

In engineered wood products (EWPs), adhesives play an essential role particularly by helping save wood, making the structure light and robust, and moderating the expansion and contraction due to the inherent moisture. Although there are many advantages associated with EWPs...

Publication date
10 Mar 2021

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General-purpose Robot for Object-retrieval in Warehouses

The current boom in e-commerce is challenging the logistics industry because shipment volumes are growing rapidly and online retail typically requires more logistical work per item compared to traditional brick and mortar retail. Manual picking is currently preferred when the...

Publication date
10 Mar 2021

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Generation of Quantum multi-Phonon states in a mechanical oscillator

The main objective of the QuPhon research action is to develop a novel hybrid quantum system between a mechanical oscillator and a superconducting qubit, especially focusing on the generation of nonclassical multi-phonon states in an ultra high-Q mechanical oscillator. The...

Publication date
10 Mar 2021

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Up-frameshift protein interactions in translation termination and nonsense-mediated mRNA decay

In eukaryotes, gene expression is highly regulated involving multistep pathways in which mRNA plays a crucial role. Cells have evolved surveillance mechanisms able to detect and degrade defective transcripts. Nonsense-mediated mRNA decay (NMD) is a mRNA surveillance mechanism...

Publication date
10 Mar 2021

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The role of microbial and invertebrate activities in shaping Alpine Soil Respiration: current state and future scenarios

The belowground production of CO2 in soil (soil respiration, SR) represents an important terrestrial carbon source. Being correlated with soil temperature, SR is expected to exacerbate climate change. In addition, SR is expected to change considerably and in a patchy manner...

Publication date
10 Mar 2021

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