We are looking for a Cellular Biologist or Biochemist with interest to understand gluten-related disorders using a translational approach

Project Description

Gliadin and its 33-mer fragment have a central pathogenic role in the context of gluten-related disorders, a group of immunological diseases with a high prevalence in Western societies (1-7%). The aim of the present project is to elucidate the molecular, structural and supramolecular basis of 33-mer oligomerization and the role of the 33-mer nanostructures in the context of epithelial cells and macrophages. The present project combines different chemical and biological methodologies and approaches by including peptide chemistry, structural and supramolecular characterization methods, cellular biology approaches, proteomics, and super-resolution optical microscopy. Our findings will open new avenues in the understanding of gluten-related disorders directed towards the design of new therapeutic targets beyond the gluten-free diet.

Candidate Profile

Master in molecular cell biology techniques with experience in cell culture. Self-motivated person with the capacity to work independently as well as in an interdisciplinary team. During the internship, the principal duties will be related to cell culture and biophysical characterization using different spectroscopical and microscopical techniques. We are offering an initial internship for 2 months. After this period, it would be possible to conduct your doctoral studies at Bielefeld University, Germany.

 

If you are interested send your CV and cover letter with the name of two references to:

Dr. Veronica I. Dodero

Bielefeld University, Germany

veronica.dodero@uni-bielefeld.de